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For clinicians with patients requiring soft-tissue repair, Restrata is a non-biologic, hybrid-scale fiber matrix engineered to be similar to human ECM that activates granulation tissue in refractory wounds while maintaining tensile strength with flexibility.

Restrata is a revolution in soft-tissue repair.

Restrata is a fully-synthetic, fully resorbable, hybrid-scale fiber matrix whose  architecture resembles human ECM and supports cell ingrowth, retention, and differentiation. Representing a new approach to the treatment of acute and chronic wounds, Restrata utilizes the advantages of synthetic construction to launch a new era in healing.

Composed of non-woven, resorbable fibers, Restrata’s unique properties enable it to resist enzymatic degradation and persist in the wound bed, providing a porous scaffold for cellular infiltration and vascularization before completely degrading via hydrolysis. 

Restrata represents a revolution in soft-tissue repair. Proven to provide healing in refractory wounds1, suitable for patients with ethical or religious objections to skin grafts, and without the special storage and handling requirements of traditional biologics, Restrata is a breakthrough in patient care.


1. Regulski, Matthew J., and Matthew R. MacEwan. "Implantable Nanomedical Scaffold Facilitates Healing of Chronic Lower Extremity Wounds." Wounds: a compendium of clinical research and practice 30.8 (2018): E77-E80.

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Use Cases

Chronic, Diabetic Foot Ulcers
For clinicians looking for a solution to chronic, diabetic foot ulcers, Restrata has been shown to provide healing in refractory wounds. Many diabetic patients struggle with ulcers that fail to respond to traditional graft treatments for a variety of reasons. Restrata has been shown to provide healing for patients with chronic ulcers that are resistant to other treatments.
Surgical Uses
Many patients face post-surgical wounds that are slow to heal or do not respond to traditional treatment methods. Clinicians searching for an alternative treatment for these patients may find a solution in Restrata. Restrata has been used in conjunction with a variety of surgical procedures, including limb salvage and amputation situations, as well as traumatic crush injuries, burns, and more.
Pressure Ulcers
Improper off-loading, common with patients recovering from knee surgery, may result in pressure ulcers. Restrata has been used to treat and heal these post-surgical complications, including some patients for whom prior treatment options did not help.

Frequently Asked Questions

For what uses is Restrata indicated?

Restrata is indicated for several uses, including those listed below. 

  • Partial and full thickness wounds
  • Pressure sores / ulcers
  • Venous ulcers
  • Diabetic ulcers
  • Tunneled / undermined wounds
  • Surgical wounds (e.g., donor site / grafts, post-laser surgery, post-Mohs surger, podiatric wounds, dehisced wounds)
  • Trauma wounds (e.g., abrasions, lacerations, partial thickness burns, skin tears)
  • Draining wounds

For a full list and additional information, please view our Restrata Indications for Use document.

Has Restrata been used in conjunction with Negative Pressure Wound Therapy?

Restrata has been used in conjunction with Negative Pressure Wound Therapy. For best results, ensure that Restrata is adequately fenestrated and the pressure is reduced.

How do I store Restrata?

Restrata has a two-year shelf life from the packaging date when stored at ambient temperatures. Refer to the expiration date on the product box for details. There are no special storage or handling requirements. Store at room temperature and avoid excessive heat or humidity.

Is there a specific requirement for applying Restrata (i.e. top or bottom)?

No, there is no specific orientation required for application.

Should I remove partially resorbed Restrata?

Pieces of Restrata that are adherent to the wound should be left in place. Pieces that are non-adherent to the wound should be removed and the wound debrided. Re-apply Restrata as needed. 

What sizes of Restrata are available?

Restrata is available in several sizes to reduce waste. Currently, the following sizes are available:

  • 10 x 12.5cm (4 x 5in)

  • 7.5 x 7.5cm (3 x 3in)

  • 5.0 x 5.0cm (2 x 2in)

  • 2.5 x 7.5cm (1 x 3in)

  • 2.5 x 5cm (1 x 2in)

  • 2.5 x 2.5cm (1 x 1in)

What types of dressings can be applied over Restrata?
  • Primary dressing: Non-adherent dressing.

  • Secondary dressings: For dry to light exudate, adding hydrogel is recommended. For moderate to heavy exudate, fenestrate Restrata to allow for drainage to pass through and utilize appropriate absorptive dressing.

  • Dressing products can be used safely after application of Restrata.

  • It is recommended that clinicians manage primary and secondary dressing changes as appropriate.

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Revolutionizing Healing. Changing Lives.
Cerafix®, Covora®, and Restrata® are registered trademarks of Acera Surgical Inc.