Results
• At Week 2, a 16.6% average reduction in wound surface area and a 20.4% reduction in wound depth was observed.
• At Week 6, an 81.1% average reduction in wound surface area and a 78.4% reduction in wound depth was observed.
• At Week 12, there was an average 98.2% reduction in wound surface area and a 95.2% reduction in wound depth, with two of three cases achieving full closure. (Patient 2 achieved full closure at Week 14.)
Conclusion
This retrospective case series evaluated the utility of MiniMatrix, a dispersible form factor of Restrata, in its application to lower extremity wounds with irregular and complex topographies. Lower extremity wounds have shown to be difficult to treat effectively. With co-morbidities negatively impacting wound healing progression, coupled with the complex etiologies of many lower extremity defects, health care professionals have struggled to find consistent, reliable treatment protocols to successfully treat these wound types. 9 The findings present in this white paper underscore the evolving potential of MiniMatrix in advancing clinical outcomes for health care professionals and their patients. Although a limitation of this case series is present in the number of patients evaluated (n=3), the positive results observed within this case series demonstrate how these treatment methods can offer an innovative, yet practical, clinical solution to treating these lower extremity wounds.