Surgical Wound Post-Cancer Resection

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Patient History

The patient has a prior history of kidney transplant on immunomodulators with tacrolimus to prevent rejection with side effects, including skin malignancy in sunexposed areas. Prior skin cancers across the right cheek and left anterior scalp. The patient had an excision of melanoma on the left parietal scalp. Previous treatments included a competitive wound matrix applied to the exposed scalp, which failed. The patient also has a history of poor vascular status, requiring bilateral above-the-knee amputations due to poor circulation and related foot wounds.*

Treatment

The patient presented with a full-thickness surgical wound post-melanoma excision. The
patient had surgical debridement of the soft tissue defect. Post debridement, RestrataSheet was applied over the soft tissue defect, followed by a non-adherent and bolstered before leaving the OR. Additional applications of Restrata MiniMatrix were applied in the outpatient setting at Week 5 and Week 9. **

Conclusion

Due to the patient’s comorbidities, the soft tissue defect was unable to close after treatment with other advanced wound care modalities. Over 11 weeks, with 3 Restrata applications, the wound was able to close via secondary intention. Restrata provided a viable option for surgical wounds post-cancerous excisions.

Week 0

Patient Presents, Surgical Excision, 1st Restrata (Sheet) Application

Week 1

Week 2

Week 4

2nd Restrata (MiniMatrix) Application

Week 5

1 week post 2nd application

Week 6

2 weeks post 2nd application

Week 9

3rd Restrata (MiniMatrix) application

Week 10

Week 11

Deemed closed

*MKG-30148

**Disclaimer: Restrata has not been studied in wounds that extend into the tendon, muscle, joint capsule, or bone. Please refer to the Instructions for Use for a full list of indications, contraindications, precautions, and warnings.

Related Clinical Case Studies

Full-Thickness Scalp Defect

One application of Restrata was used to generate a healthy granulation base and allowed the patient to receive a split-thickness skin graft. Full closure was achieved in 10 weeks.

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