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Reconstruction of Hidradenitis Suppurativa Resection

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Patient History

A 65-year-old female presented with a non-healing wound in the left axilla resulting from hidradenitis suppurativa (HS), a chronic inflammatory skin condition. After prior treatment attempts of other commercially available products, the wound remained open for several months, raising concern over contamination risk. Restrata was chosen to facilitate soft tissue repair due to its ability to perform in hostile wound environments.^1,2

Treatment

Following surgical debridement of HS, Restrata MiniMatrix was sparingly applied and covered with a non-adherent outer dressing followed by negative pressure wound therapy (NPWT).

Conclusion

A single application of Restrata MiniMatrix facilitated rapid and robust tissue formation³ over the non-healing wound. Significant wound reduction was achieved, with final closure via secondary intention..

POST DEBRIDEMENT

Soft tissue loss of left axilla.

DAY 0

Restrata MiniMatrix sparingly applied to ~125 cm2 wound.

DAY 6

Early incorporation of Restrata MiniMatrix.

DAY 10

Early formation of vascularized tissue.

DAY 17

Well vascularized tissue ready for a skin graft.

DAY 35

Wound significantly decreased to ~10 cm2 and left to heal via secondary intention.

REFERENCES
1. Sallade E, Grimes D, Jeng L, et al. (December 06, 2023) Antimicrobial Effectiveness Testing of Resorbable Electrospun Fiber Matrix per United States Pharmacopeia (USP) <51>. Cureus 15(12): e50055. doi:10.7759/cureus.50055.
2. Fernandez L, Schar A, Matthews M, Kim PJ, Thompson C, Williams N, Stutsman M. Synthetic Hypbrid-Scale Fiber Matrix in the Trauma and Acute Care Surgical Practice. Wounds. 2021 Sept;33(9):237-244. PMID:
34734842.
3. MacEwan MR, MacEwan S, Kovacs TR, Batts J. What Makes the Optimal Wound Healing Material? A Review of Current Science and Introduction of a Synthetic Nanofabricated Wound Care Scaffold. Cureus. 2017;9(10):e1736. Published 2017 Oct 2. doi:1-:7799/cureus.1736.

Restrata has not been studied in wounds that extend into the tendon, muscle, joint capsule, or bone. Restrata should not be applied until excessive exudate, bleeding, acute swelling, and infection is controlled. Please refer to the Instructions for Use for a full list of indications, contraindications, precautions, and warnings.

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